enalaprilat

Ligand id: 6332

Name: enalaprilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 106.94
Molecular weight 348.17
XLogP 3.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Administered as enalapril to treat hypertension.
Mechanism Of Action and Pharmacodynamic Effects
Enalaprilat inhibits the conversion of angiotensin I to angiotensin II, a key component of the renin-angiotensin-aldosterone system (a hormonal system which regulates blood pressure and fluid balance).