abciximab

Ligand id: 6584

Name: abciximab

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Summary of Clinical Use
Used in the management of cardiac ischemia.
Mechanism Of Action and Pharmacodynamic Effects
Abciximab is an antagonist of the integrin, glycoprotein IIb/IIIa receptor (CD41, aka integrin αIIbβ3). Abciximab prevents fibrinogen-mediated activation of αIIbβ3 on platelets and this action reduces platelet aggregation and clot formation.
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