Ligand id: 6791

Name: acarbose

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 19
Hydrogen bond donors 14
Rotatable bonds 9
Topological polar surface area 321.17
Molecular weight 645.25
XLogP -5.53
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Drug has antihyperglycemic actionand is used to treat type 2 diabetes mellitus and, in some countries, prediabetes.
Mechanism Of Action and Pharmacodynamic Effects
A starch blocker, which inhibits alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates and thus reduces increased blood-glucose concentrations following carbohydrate load.