Ligand id: 685

Name: calcitonin

Abbreviated name: CT

Species: Human

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Mechanism Of Action and Pharmacodynamic Effects
Calcitonin binds to the calcitonin receptor (found primarily in osteoclasts) and enhances the production of vitamin D producing enzymes. This results in increased calcium retention and enhanced osteogenesis and bone density. Binding of calcitonin to its receptor also activates the adenylyl cyclase and phosphatidyl-inositol-calcium signalling pathways.