capromab   Click here for help

GtoPdb Ligand ID: 6878

Synonyms: capromab pendetide | CYT-351 | CYT-356 | Indium In 111 capromab | ProstaScint®
Approved drug
capromab is an approved drug (FDA (1996))
Compound class: Antibody
Comment: Used as an imaging agent (ProstaScint) by labelling with the radionuclide Indium-111 (using capromab pendetide, where the pendetide is the chelating agent for the radiolabel).
No information available.
Summary of Clinical Use Click here for help
Used in diagnostic imaging of metastatic prostate cancer in newly diagnosed, high risk patients [1-2].
Mechanism Of Action and Pharmacodynamic Effects Click here for help
This antibody is designed to bind to FOLH1 (prostate-specific membrane antigen, which can be found in the M28: Aminopeptidase Y enzyme family in this database) on the surface of prostate cells.