basiliximab

Ligand id: 6879

Name: basiliximab

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Summary of Clinical Use
Prophylaxis of acute organ rejection in adults following cadaveric- or living-donor renal transplantation
Mechanism Of Action and Pharmacodynamic Effects
Abrogates the critical cellular immune response involved in allograft rejection by acting as a functional IL-2 receptor antagonist, thereby inhibiting IL-2-mediated activation of lymphocytes.
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