flutamide

Ligand id: 6943

Name: flutamide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 72.24
Molecular weight 276.07
XLogP 3.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Flutamide may be used to treat locally confined metastatic prostate cancers.
Mechanism Of Action and Pharmacodynamic Effects
Flutamide blocks the action of endogenous and exogenous testosterone by binding to the androgen receptor.