filgrastim

Ligand id: 6968

Name: filgrastim

No information available.
Summary of Clinical Use
This drug is used to increase white cells counts in various situations: prior to a bone marrow transplant (eg before donating bone marrow), post-bone marrow transplant or during certain cancer treatments.
Mechanism Of Action and Pharmacodynamic Effects
This drug mimics the action of endogenous human granulocyte colony stimulating factor (G-CSF), controlling the proliferation and maturation of neutrophils from progenitor cells and in addition stimulating the release of neutrophils from bone marrow storage pools. We would expect the affinity for this drug at the G-CSF receptor to be similar to that of the endogenous ligand, however this data remains elusive. Therefore we have not tagged a primary target for this drug.