Ligand id: 7021

Name: AZ505

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 14
Topological polar surface area 102.93
Molecular weight 576.23
XLogP 3.93
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
AZ505 is a substrate competitive inhibitor of SMYD2, which binds in the peptide binding groove of the enzyme [1].