travoprost

Ligand id: 7102

Name: travoprost

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: travoprost

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 96.22
Molecular weight 500.24
XLogP 5.18
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to decrease elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Mechanism Of Action and Pharmacodynamic Effects
Travoprost free acid is a selective FP prostanoid receptor (PTGFR) agonist, which reduces intraocular pressure by increasing the outflow of aqueous fluid from the eye.
External links