bretylium

Ligand id: 7130

Name: bretylium

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 0
Molecular weight 242.05
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used for emergency treatment of ventricular tachycardia and ventricular fibrillation. However, there is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation
Mechanism Of Action and Pharmacodynamic Effects
May act though inhibition of voltage-gated K+ channels or by binding extracellularly to Na+/K+-ATPases.