bretylium

Ligand id: 7130

Name: bretylium

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 0
Molecular weight 242.05
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
[(2-bromophenyl)methyl](ethyl)dimethylazanium
International Nonproprietary Names
INN number INN
927 bretylium tosilate
Synonyms
ASL-603 | bretylium tosylate | Bretylol®
Database Links
CAS Registry No. 61-75-6
ChEMBL Ligand CHEMBL1199080
DrugBank Ligand DB01158
GtoPdb PubChem SID 178103706
PubChem CID 2431
Search Google for chemical match using the InChIKey AAQOQKQBGPPFNS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AAQOQKQBGPPFNS
Search PubMed clinical trials bretylium tosilate
Search PubMed titles bretylium tosilate
Search PubMed titles/abstracts bretylium tosilate
Search UniChem for chemical match using the InChIKey AAQOQKQBGPPFNS-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AAQOQKQBGPPFNS
Wikipedia Bretylium
Comments
Bretylium is a substrate for the noradrenaline transporter so it accumulates inside nerve terminals which have this transporter. This accumulation underlies its inhibitory action on the sympathetic nervous system. Bretylium tosylate is no longer available in the US.