methixene

Ligand id: 7232

Name: methixene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 28.54
Molecular weight 309.16
XLogP 5.79
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Anticholinergic activity is used to treat Parkinson disease, hyperactivity, anxiety and insomnia. The drug is also used to treat allergy symptoms.
Mechanism Of Action and Pharmacodynamic Effects
Methixene blocks the action of endogenous histamine at the histamine H1 receptor. Anticholinergic activity underlies the drugs additional actions.