alimemazine

Ligand id: 7237

Name: alimemazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 31.78
Molecular weight 298.15
XLogP 4.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat allergic pruritis and motion sickness. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
Alimemazine blocks the action of endogenous histamine at the histamine H1 receptor. Anticholinergic activity underlies the drugs additional actions.