Ligand id: 7339

Name: CHF-5074

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 37.3
Molecular weight 324.01
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
CHF5074 was well tolerated in Mild Congitive Impairment patients and dose-dependently affects central nervous system biomarkers of neuroinflammation, indicative of efficacy for Alzheimer's [1]