Ligand id: 7441

Name: icosapent

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 15
Topological polar surface area 26.3
Molecular weight 330.26
XLogP 8.77
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved to treat patients with severely high triglyceride levels (hypertriglyceridemia) [1-2], in conjunction with a low-fat and low-cholesterol diet.
Mechanism Of Action and Pharmacodynamic Effects
The molecular mechanism whereby icosapent reduces triglyceride levels is poorly understood. See the DrugBank link on the Summary tab of this ligand page for further details.
External links