Ligand id: 7441

Name: icosapent

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 15
Topological polar surface area 26.3
Molecular weight 330.26
XLogP 8.77
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Ballantyne CM, Braeckman RA, Soni PN. (2013)
Icosapent ethyl for the treatment of hypertriglyceridemia.
Expert Opin Pharmacother, 14 (10): 1409-16. [PMID:23701295]
2. Bays HE, Braeckman RA, Ballantyne CM, Kastelein JJ, Otvos JD, Stirtan WG, Soni PN. (2012)
Icosapent ethyl, a pure EPA omega-3 fatty acid: effects on lipoprotein particle concentration and size in patients with very high triglyceride levels (the MARINE study).
J Clin Lipidol, 6 (6): 565-72. [PMID:23312052]