Ligand id: 7473

Name: fesoterodine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 49.77
Molecular weight 411.28
XLogP 7.54
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved to treat the symptoms (increased urinary frequency and/or urgency and/or urgency incontinence) that occur in patients with overactive bladder syndrome.
Mechanism Of Action and Pharmacodynamic Effects
Fesoterodine is an antagonist of muscarinic acetylcholine receptors M2 and M3. Antimuscarinic drugs are the main treatment option for overactive bladder syndrome [1]. Drug action relaxes the smooth muscle of the bladder wall, increasing volume and decreasing urgency.
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