Ligand id: 7554

Name: dexmethylphenidate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 38.33
Molecular weight 233.14
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat attention deficit hyperactivity disorder (ADHD) in adults and children >6 years old, although this enantiomer is used less often than the racemic mixture, methylphenidate.
Mechanism Of Action and Pharmacodynamic Effects
Dexmethylphenidate is a norepinephrine-dopamine reuptake inhibitor (NDRI) which acts as a psychostimulant.