perospirone

Ligand id: 7556

Name: perospirone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 84.99
Molecular weight 426.21
XLogP 3.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat schizophrenia. However, there is no information regarding approval for clinical use of this drug on the US FDA or European Medicines Agency (EMA) websites. Individual national approval agencies may have granted marketing authorisation. The international drug listing on the FDA website only lists China and Japan as countries where this drug may be used.
Mechanism Of Action and Pharmacodynamic Effects
This drug has multifunctional activity. It has been reported as an antagonist at dopamine D1, D2 and D3 receptors, serotonin 5-HT2 and 5-HT3 receptors, α1-adrenoceptors and a partial agonist at the 5-HT1A receptor. The combined effect of this is to improve psychotic symptoms.