amfenac

Ligand id: 7565

Name: amfenac

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 80.39
Molecular weight 255.09
XLogP 3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Appears to be licensed only in Japan. As with its prodrug, nepafenac, amfenac may be used to treat the pain and inflammation caused by cataract surgery [1].
Mechanism Of Action and Pharmacodynamic Effects
As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity.