Ligand id: 7565

Name: amfenac

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 80.39
Molecular weight 255.09
XLogP 3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Jones BM, Neville MW. (2013)
Nepafenac: an ophthalmic nonsteroidal antiinflammatory drug for pain after cataract surgery.
Ann Pharmacother, 47 (6): 892-6. [PMID:23715071]
2. Welstead Jr WJ, Moran HW, Stauffer HF, Turnbull LB, Sancilio LF. (1979)
Antiinflammatory agents. 1. Synthesis and antiinflammatory activity of 2-amino-3-benzoylphenylacetic acid.
J. Med. Chem., 22 (9): 1074-9. [PMID:490552]