Ligand id: 7602

Name: ropivacaine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 32.34
Molecular weight 274.2
XLogP 3.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Ropivacaine is a local anaesthetic drug used for procedures requiring spinal block (epidural) anaesthesia.
Mechanism Of Action and Pharmacodynamic Effects
Blocks sodium channel alpha subunits on affected nerve fibers, thereby preventing the generation and conduction of nerve impulses.
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