Ligand id: 7670

Name: blonanserin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 19.37
Molecular weight 367.24
XLogP 6.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Blonanserin is approved in Japan for the treatment of schizophrenia.
Mechanism Of Action and Pharmacodynamic Effects
Blonanserin acts as a mixed serotonin 5-HT2A and dopamine D2 receptor antagonist, with some additional antagonism of α1-adrenoceptors [2].