Ligand id: 7698

Name: AZD1208

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 100.73
Molecular weight 379.14
XLogP 4.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
AZD1208 was developed with the aim of inhibiting abberant PIM kinase activity which has been reported to be upregulated in several types of leukemias and lymphomas.