Ligand id: 7879

Name: BMS-690514

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 100.94
Molecular weight 368.2
XLogP 1.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
BMS-690514 is currently under investigation as an oral agent for the treatment of solid tumors. Phase II clinical trial NCT01167244 for non-small cell lung cancer (NSCLC) previously treated with gefitinib or erlotinib and are genotypically EGFR mutation positive was completed in 2011.