Ligand id: 7885

Name: ENMD-2076

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 72.97
Molecular weight 375.22
XLogP 5.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
ENMD-2076 is being assessed in Phase II clinical trials for indications including ovarian clear cell cancers (NCT01914510), advanced/metastatic soft tissue sarcoma (NCT01719744) and advanced fibrolamellar carcinoma (NCT02234986).