Ligand id: 8060

Name: AMG-900

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 139.97
Molecular weight 503.15
XLogP 6.84
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Phase I clinical trials in advanced solid tumours (NCT00858377) and acute myeloid leukemia (NCT01380756) are ongoing..