compound 27 [PMID: 19854648]

Ligand id: 8168

Name: compound 27 [PMID: 19854648]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 76.24
Molecular weight 403.05
XLogP 3.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
The rationale behind HRI inhibition is that this action will induce increased globin production and hemeoglobin levels as the basis for improving oxygenation in anaemic patients [1].