Ligand id: 8463

Name: amelubant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 100.87
Molecular weight 538.25
XLogP 9.67
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Amelubant (BIIL 284) reached Phase II clinical trial for inflammatory conditions including chronic obstructive pulmonary disease (COPD), broncial asthma and rheumatoid arthritis (RA).