apalutamide

Ligand id: 9043

Name: apalutamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 121.42
Molecular weight 477.09
XLogP 3.78
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Apalutamide (using research codes ARN-509 and JNJ-56021927) and is being evaluated in several Phase III clinical trials in prostate cancer patients. Click here to link to ClinicalTrials.gov's list of Phase III apalutamide trials.