diamorphine

Ligand id: 9082

Name: diamorphine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: diamorphine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 65.07
Molecular weight 369.16
XLogP 2.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Under the name diamorphine, heroin is a legal prescription drug in the United Kingdom. May be used for the treatment of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnoea in acute pulmonary oedema. Diamorphine may be given by the intramuscular, intravenous, subcutaneous or oral routes. A nasal spray formulation is available for use in children for treatment of acute severe nociceptive pain within a hospital setting.