Ligand id: 9089

Name: etomoxir

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 48.06
Molecular weight 326.13
XLogP 3.96
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Etomoxir reached Phase II clinical trial for type 2 diabetes and heart failure. Development was terminated due to an unacceptable risk of the treatment causing severe hepatotoxicity.