EPZ020411

Ligand id: 9243

Name: EPZ020411

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 71.64
Molecular weight 442.29
XLogP 2.98
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
PRMT6 overexpression has been reported in several cancer types, so research and medicinal chemistry effort has been devoted to the development of pharmacological PRMT6 inhibitor compounds as leads for novel anti-cancer therapeutics.