Ligand id: 9243

Name: EPZ020411

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 71.64
Molecular weight 442.29
XLogP 2.98
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Mitchell LH, Drew AE, Ribich SA, Rioux N, Swinger KK, Jacques SL, Lingaraj T, Boriack-Sjodin PA, Waters NJ, Wigle TJ et al.. (2015)
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
ACS Med Chem Lett, 6 (6): 655-9. [PMID:26101569]