Ligand id: 9256

Name: AZD8848

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 135.38
Molecular weight 569.33
XLogP 2.67
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
AZD8848 is under development as a topically (intranasally) administered therapy for seasonal allergic rhinitis, having completed Phase 1 clinical trials. Phase 2 results from NCT00770003/NCT00688779 are reported in [3] and [4].