abiraterone acetate

Ligand id: 9288

Name: abiraterone acetate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 39.19
Molecular weight 391.25
XLogP 6.53
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Abiraterone acetate is used to treat refractory prostate cancer in combination with prednisone or prednisolone. In May 2018, the US FDA approved a novel, ultramicrosized formulation of abiraterone acetate (Yonsa®) for the treatment of metastatic castration-resistant prostate cancer, that is to be used in combination with methylprednisolone.
External links