compound 6 [PMID: 25874594]

Ligand id: 9178

Name: compound 6 [PMID: 25874594]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 67.43
Molecular weight 268.18
XLogP 3.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Compound 6 is an inhibitor of intracellular N-Acylethanolamine acid amidase (NAAA) that exhibits anti-inflammatory effects in both mouse models and human macrophages [2].