compound 6 [PMID: 25874594]

Ligand id: 9178

Name: compound 6 [PMID: 25874594]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 67.43
Molecular weight 268.18
XLogP 3.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Piomelli D. et al.. (2014)
Carbamate derivatives of lactam based n-acylethanolamine acid amidase (NAAA) inhibitors.
Patent number: WO2014144836. Assignee: Regents Of The University Of California. Priority date: 15/03/2013. Publication date: 18/09/2014.
2. Ribeiro A, Pontis S, Mengatto L, Armirotti A, Chiurchi├╣ V, Capurro V, Fiasella A, Nuzzi A, Romeo E, Moreno-Sanz G et al.. (2015)
A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation.
ACS Chem. Biol., 10 (8): 1838-46. [PMID:25874594]