Ligand id: 9266

Name: CNX-774

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 130.16
Molecular weight 499.18
XLogP 4.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
CNX-774 is a selectiveBTK inhibitor, that was tested preclinically for autoimmune diseases, and B-cell non-Hodgkin's lymphoma.