Ligand id: 9266

Name: CNX-774

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 130.16
Molecular weight 499.18
XLogP 4.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Barf T, Kaptein A. (2012)
Irreversible protein kinase inhibitors: balancing the benefits and risks.
J. Med. Chem., 55 (14): 6243-62. [PMID:22621397]