Ligand id: 9357

Name: BI605906

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 156
Molecular weight 432.11
XLogP 1.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
BI605906 is an inhibitor of IKKβ (IKBKB) [1]. Inhibitors of the kinase activity of the IκB kinase (IKK) complex are in development as novel therapeutics for IKK mediated diseases including autoimmune, inflammatory and cardiovascular diseases, and cancer.