Ligand id: 9586

Name: AZ7188

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 36.1
Molecular weight 262.11
XLogP 3.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Activation of PARs elicits a cellular cascade in response to inflammatory signals and other stimuli. The development of small molecule antagonists to inhibit this response is the subject of major pharmaceutical research efforts.