Synonyms: A-62254 | A62254 | Abbott 62254 | Omniflox®
temafloxacin is an approved drug (FDA (1992))
Compound class:
Synthetic organic
Comment: Temafloxacin (A-62254) is a fluoroquinolone antibacterial [2].
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References |
1. Chu DT, Nordeen CW, Hardy DJ, Swanson RN, Giardina WJ, Pernet AG, Plattner JJ. (1991)
Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temafloxacin hydrochloride. J Med Chem, 34 (1): 168-74. [PMID:1846917] |
2. Domagala JM, Bridges AJ, Culbertson TP, Gambino L, Hagen SE, Karrick G, Porter K, Sanchez JP, Sesnie JA, Spense FG et al.. (1991)
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship. J Med Chem, 34 (3): 1142-54. [PMID:1848296] |