Synonyms: TNP-2198
Compound class:
Synthetic organic
Comment: Rifasutenizol (formerly TNP-2198) is a rifamycin-nitroimidazole conjugate antibacterial compound [1]. Note that there is some ambiguity in the literature and online chemistry resources as to the precise stereochemistry of this ligand. We have drawn the structure as depicted in its INN record.
|
|
References |
1. Ma Z, He S, Yuan Y, Zhuang Z, Liu Y, Wang H, Chen J, Xu X, Ding C, Molodtsov V et al.. (2022)
Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. J Med Chem, 65 (6): 4481-4495. [PMID:35175750] |