Ligand id: 1408

Name: ACPT-I

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 137.92
Molecular weight 217.06
XLogP -4.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Acher FC, Tellier FJ, Azerad R, Brabet IN, Fagni L, Pin JP. (1997)
Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes.
J Med Chem, 40: 3119-3129. [PMID:9301676]
2. de Colle C, Bessis AS, Bockaert J, Acher F, Pin JP. (2000)
Pharmacological characterization of the rat metabotropic glutamate receptor type 8a revealed strong similarities and slight differences with the type 4a receptor.
Eur J Pharmacol, 394: 17-26. [PMID:10771029]