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Compound class:
Peptide or derivative
Comment: This synthetic peptide is an analogue of the conserved cyclic hexapeptide portion of urotensin-II (amino acids 5-10 of the endogenous peptide). A histidine replaces the valine in the carboxy terminal position 11 of the natural ligand.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Coy DH, Rossowski WJ, Cheng BL, Taylor JE. (2002)
Structural requirements at the N-terminus of urotensin II octapeptides. Peptides, 23 (12): 2259-64. [PMID:12535707] |
