Ligand id: 2828

Name: daidzein

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 66.76
Molecular weight 254.06
XLogP 2.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Atkinson C, Frankenfeld CL, Lampe JW. (2005)
Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health.
Exp. Biol. Med. (Maywood), 230 (3): 155-70. [PMID:15734719]
2. Dang Z, Löwik CW. (2004)
The balance between concurrent activation of ERs and PPARs determines daidzein-induced osteogenesis and adipogenesis.
J. Bone Miner. Res., 19 (5): 853-61. [PMID:15068509]
3. Suetsugi M, Su L, Karlsberg K, Yuan YC, Chen S. (2003)
Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors.
Mol. Cancer Res., 1 (13): 981-91. [PMID:14638870]