compound 8 [Brinkman et al., 1996]

Ligand id: 3066

Name: compound 8 [Brinkman et al., 1996]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 21.26
Molecular weight 357.21
XLogP 6.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Brinkman JA, Damon RE, Fell JB, Perez LB, Scallen TJ, Vedamanda TR. (1996)
Squalene synthase inhibitors: isosteric replacements of the farnesyl chain of benzyl farnesyl amine.
Bioorg. Med. Chem. Lett., 6 (21): 2491-2494.