Ligand id: 4035

Name: camicinal

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 47.61
Molecular weight 424.26
XLogP 4.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Barshop K, Kuo B. (2015)
The investigational drug camicinal for the treatment of gastroparesis.
Expert Opin Investig Drugs, 24 (1): 133-140. [PMID:25341626]
2. Peeters TL. (2015)
Gastrointestinal hormones and gut motility.
Curr Opin Endocrinol Diabetes Obes, 22 (1): 9-13. [PMID:25517024]
3. Sanger GJ, Westaway SM, Barnes AA, Macpherson DT, Muir AI, Jarvie EM, Bolton VN, Cellek S, Näslund E, Hellström PM et al.. (2009)
GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.
Neurogastroenterol. Motil., 21 (6): 657-64, e30-1. [PMID:19374732]